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Baffled by some of the words? Check out the Key terms page 

Clinical Obesity 

overweight to a degree which causes medical complications

KEY CONCEPT: 

Causes and consequences of occlusion of the coronary arteries.

What are coronary arteries? 

Coronary arteries supply blood to the heart muscle. Like all other tissues in the body, the heart muscle needs oxygen-rich blood to function, and oxygen-depleted blood must be carried away. The coronary arteries run along the outside of the heart and have small branches that dive into the heart muscle to bring it blood.

 

Figure 1 : coronary arteries

The function of Coronary artieries is to carry blood which contains nutrients vital to the functioning of the heart muscle in addition to oxygen. 

Their Function? 

Occlusion or blockage can either be PARTIAL OR complete 

 

Random complete occlusion of coronary arteries lead to the death of the area of muscle which depends on the artery. This is known as a myocardinal infarct. 

 

Partial occlusion/ blockage takes place due to the eventual accumulation of plaques which are plentiful in cholestrol. This can be exacerbated by blood clots forming on the plaques - (coronary thrombosis) 

 

Partial occlusion of the blood flow; refers to the heart attempting to work harder, and increasing the reate at which the supply of oxygen is transported in the blood; however when this  becomes insufficient; the patient experiences pain (angina). 

 

Coronary occlusion can take place less widely because of muscles in the artery wall momentarily experiencing a spasm due to the inflammation of the coronary wall. 

 

The cause of the formation of the chlostrol rich plaques is impacted by a variety of "risk"factors. 

 

1) As age increases, people become more likely to develop this condition. In some families genetics are invovled, as there is an inherited risk of developing the condition whilst at an early age. 

 

Dietary animal fat and dietary cholestrol impacts are not as certain, however a smaller consumption is recommended. 

 

Another preventative measure is avoiding becoming overweight in addition to excercising regularly. 

 

Another risk is raised blood levels of cholestrol, especially in relation with a substance in the blood known as the high density lipoprotein (HDL) 

 

 

Smoking and High Blood Pressure also increase the risk of developing coronary occlusion. 

 

Specific chronic diseases also increase the potentiality of getting coronary artery disease. 

 

 

Consequence and Causes 

Treatment selection is dependent on the nature/ sites of the occlusion. 

 

Partial occlusion can be treated with medication; such as th enitrate group of drugs (glyceryl trinitrate OR isorbide mononitrate- this increases the diameter of the artery and also increases the flow of oxygen which contains blood) 

 

Medication can also be used to hinder the heart rate speeding up; this also controls the heart muscle's demand for oxygen. 

 

 

 

Treatment Options 

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